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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T67698 | p53-Mdm2 inhibitor 4 | Mdm2 , p53 | |
p53-Mdm2 inhibitor 4 inhibits the p53-MDM2 protein-protein interaction. | |||
T63438 | Rel-MDM2/4-p53-IN-3 | ||
rel-MDM2/4-p53-IN-3 is an MDM2/4-p53 protein-protein interaction (PPI) inhibitor that acts on MDM2-p53 and MDM4-p53 with IC50 values of 18.5 nM and 14.8 nM, respectively. rel-MDM2/4-p53-IN-3 can be used to study cancers,... | |||
T74936 | MDM2/4-p53-IN-3 | ||
MDM2/4-p53-IN-3, an inhibitor of MDM2/4-p53 protein-protein interactions (PPIs), exhibits potent activity with IC50 values of 18.5 nM for MDM2-p53 and 14.8 nM for MDM4-p53. This compound is applicable in cancer research,... | |||
T63748 | Rel-MDM2/4-p53-IN-2 | ||
rel-MDM2/4-p53-IN-2 (2q) is a potent dual MDM2/MDM4 inhibitor and p53 activator that acts on both the MDM2-p53 complex (IC50: 70.7 nM) and the MDM4-p53 complex (IC50: 81.4 nM). rel-MDM2/4-p53-IN-2 is capable of regulatin... | |||
T74935 | MDM2/4-p53-IN-2 | ||
MDM2/4-p53-IN-2 (2q) is a potent dual inhibitor of MDM2/MDM4 and activator of p53, demonstrating IC50 values of 70.7 nM for MDM2-p53 and 81.4 nM for MDM4-p53 complexes. It facilitates cell cycle regulation, promotes apop... | |||
T14554 | BI-0252 | Others | |
BI-0252 is an inhibitor of MDM2-p53 (IC50:4 nM). BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft. And it concomitant induction of the tumor protein p53 (TP53) target genes and markers of a... |